On working with Sasha Alexander and the chemistry between them, Harmon reveals that a few actors auditioned for the part of Maura Isles, but Alexander “kind of hit it out on the part.” Not only did she get the fact that Dr. Isles was this quirky and socially awkward scientist, but she also got the fact that Maura had friends.
Plus working together with Alexander for the past three seasons strengthened their friendship. “There was an instantaneous recognition and a friendship that’s grown and matured over the years,” pointed out Harmon.
Sasha spoke about the chemistry between her and Angie in her interview:
Was the perfect chemistry with Angie instant when you guys began working together? Did it take a bit of time for you all to gel? I mean, it looks flawless.